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Brian Henderson The Human Microbiota and Chronic Disease. Dysbiosis as a Cause of Pathology


Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species. The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease. The Human Microbiota and Human Chronic Disease: Dysbioses as a Cause of Human Pathology discusses the role of the microbiota in maintaining human health. The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease states. Divided into five sections, the text delineates the concept of the human bacterial microbiota with particular attention being paid to the microbiotae of the gut, oral cavity and skin. A key methodology for exploring the microbiota, metagenomics, is also described. The book then shows the reader the cellular, molecular and genetic complexities of the bacterial microbiota, its myriad connections with the host and how these can maintain tissue homeostasis. Chapters then consider the role of dysbioses in human disease states, dealing with two of the commonest bacterial diseases of humanity – periodontitis and bacterial vaginosis. The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The discussion moves on to the major ‘idiopathic’ diseases afflicting humans, and the potential role that dysbiosis could play in their induction and chronicity. The book then concludes with the therapeutic potential of manipulating the microbiota, introducing the concepts of probiotics, prebiotics and the administration of healthy human faeces (faecal microbiota transplantation), and then hypothesizes as to the future of medical treatment viewed from a microbiota-centric position. Provides an introduction to dysbiosis, or a disruption in the composition of the normal human microbiota Explains how microbiota-associated pathology and other chronic diseases can result from changes in general bacterial composition Explores the relationship humans have with their microbiota, and its significance in human health and disease Covers host genetic variants and their role in the composition of human microbial biofilms, integral to the relationship between human health and human disease Authored and edited by leaders in the field, The Human Microbiota and Human Chronic Disease will be an invaluable resource for clinicians, pathologists, immunologists, cell and molecular biologists, biochemists, and system biologists studying cellular and molecular bases of human diseases.

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David Fredricks N. The Human Microbiota. How Microbial Communities Affect Health and Disease


The Human Microbiota offers a comprehensive review of all human-associated microbial niches in a single volume, focusing on what modern tools in molecular microbiology are revealing about human microbiota, and how specific microbial communities can be associated with either beneficial effects or diseases. An excellent resource for microbiologists, physicians, infectious disease specialists, and others in the field, the book describes the latest research findings and evaluates the most innovative research approaches and technologies. Perspectives from pioneers in human microbial ecology are provided throughout.

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Gerald Tannock W. Understanding the Gut Microbiota


This book discusses the community of microbial species (the microbiota, microbiome), which inhabits the large bowel of humans. Written from the perspective of an academic who has been familiar with the topic for 40 years, it provides a long-term perspective of knowledge about this high profile and fast-moving topic. Building on general ecological principles, the book aims to help the reader to understand how the microbiota is formed, how it works, and what the consequences are to humans. Understanding the Gut Microbiota focuses on conceptual progress made from studies of the human bowel microbiota. Where appropriate, it draws on knowledge obtained from other animal species to provide conceptual enlightenment, but this is essentially a book about humans and their bowel microbes. Particular research approaches are recommended to fill knowledge gaps so that fundamental ecological theory and information about the microbiota can be translated into benefits for human health. The relationship between food for humans and resulting food for bowel bacteria emerges as an important topic for consideration. This concise scholarly treatise of the microbiota of the human bowel will be of great interest and use as a text and reference work for professionals, teachers and students across a wide range of disciplines, including the health sciences, general biology, and food science and technology. The provision of handy ‘explanation of terms’ means that those with a general interest in science can also read the book with enjoyment.

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Brian O’Connell The Personals


The Personals reveals how classified ads are not just a few commercial lines of text in print or online – they can be a treasure trove of fascinating human stories; stories of love, loss, loneliness, redemption and hope. Some people do Sudoku, others watch Netflix. Brian O’Connell loves the classified ads. In an era of spin doctors and press releases, celebrities and social influencers, the classified ads can open a door into the lives of ordinary people with extraordinary stories. What draws Brian to the classified ads are the intriguing human stories he finds there, the unexpected twists and turns, the personalities, the curious objects and the range of human experience waiting to be discovered. The Personals is a diverse collection of compelling stories about the people and the lives behind the small ads.

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Joe Henderson - The State Of Tenor Vol.2

Joe Henderson - The State Of Tenor

Brian Aldiss Jocasta: Wife and Mother


A Theban adventure from the master of Science-Fiction, here proving himself adept at imagining historical worlds. Part of the Brian Aldiss Collection.In Jocasta, Aldiss brings vividly to life the ancient world of dreaming Thebes: a world of sun-drenched landscapes, golden dust, sphynxes, Furies, hermaphroditic philosophers, ghostly apparitions and ambivalent gods. Jocasta is also a strikingly effective contemplation of an older world order where the human mind is still struggling to understand itself and the nature of the world around it.

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Patrick Millot Designing Human-machine Cooperation Systems


This book, on the ergonomics of human−machine systems, is aimed at engineers specializing in informatics, automation, production or robotics, who are faced with a significant dilemma during the conception of human−machine systems. On the one hand, the human operator guarantees the reliability of the system and has been known to salvage numerous critical situations through an ability to reason in unplanned, imprecise and uncertain situations; on the other hand, the human operator can be unpredictable and create disturbances in the automated system. The first part of the book is dedicated to the methods of human-centered design, from three different points of view, the various chapters focusing on models developed by human engineers and functional models to explain human behavior in their environment, models of cognitive psychology and models in the domain of automobile driving. Part 2 develops the methods of evaluation of the human−machine systems, looking at the evaluation of the activity of the human operator at work and human error analysis methods. Finally, Part 3 is dedicated to human−machine cooperation, where the authors show that a cooperative agent comprises a know-how and a so-called know-how-to-cooperate and show the way to design and evaluate that cooperation in real industrial contexts.

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Robert Henderson Mackenzie Kenneth The Marvellous Adventures and Rare Conceits of Master Tyll Owlglass

Brian Henderson Moonlighting Proteins. Novel Virulence Factors in Bacterial Infections


Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections is a complete examination of the ways in which proteins with more than one unique biological action are able to serve as virulence factors in different bacteria. The book explores the pathogenicity of bacterial moonlighting proteins, demonstrating the plasticity of protein evolution as it relates to protein function and to bacterial communication. Highlighting the latest discoveries in the field, it details the approximately 70 known bacterial proteins with a moonlighting function related to a virulence phenomenon. Chapters describe the ways in which each moonlighting protein can function as such for a variety of bacterial pathogens and how individual bacteria can use more than one moonlighting protein as a virulence factor. The cutting-edge research contained here offers important insights into many topics, from bacterial colonization, virulence, and antibiotic resistance, to protein structure and the therapeutic potential of moonlighting proteins. Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections will be of interest to researchers and graduate students in microbiology (specifically bacteriology), immunology, cell and molecular biology, biochemistry, pathology, and protein science. About the Editor Brian Henderson, Division of Infection and Immunity, University College London, London, UK

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Brian Henderson Protein Moonlighting in Biology and Medicine


The past 25 years has seen the emergence of a wealth of data suggesting that novel biological functions of known proteins play important roles in biology and medicine. This ability of proteins to exhibit more than one unique biological activity is known as protein moonlighting. Moonlighting proteins can exhibit novel biological functions, thus extending the function of the proteome, and are also implicated in the pathology of a growing number of idiopathic and infectious diseases. This book, written by a cell biologist, protein evolutionary biologist and protein bioinformatician, brings together the latest information on the structure, evolution and biological function of the growing numbers of moonlighting proteins that have been identified, and their roles in human health and disease. This information is revealing the enormous importance protein moonlighting plays in the maintenance of human health and in the induction of disease pathology. Protein Moonlighting in Biology and Medicine will be of interest to a general readership in the biological and biomedical research community.

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Prescott Robert K. Encyclopedia of Human Resource Management, Key Topics and Issues


The three volumes in The Encyclopedia of Human Resource Management offer a comprehensive review of the essential issues and most important information available on the topic. Each volume in the encyclopedia contains contributions from some of the most celebrated names in the field of human resource management (HRM) and addresses the myriad challenges faced by todays human resource professionals. Volume 1 puts the focus on the definition of terms and practices that are most relevant to todays human resource management (HRM) professionals. The contributors bring an up-to-date perspective of HRM definitions and practices and for ease of access, the terms are presented in alphabetical order. Each contributor includes the most recent research on a particular topic and summarizes a new and progressive definition of these important terms. The book begins with an enlightening discussion of the evolving practice of talent management and contains the following topics: Affirmative Action, Assessment, Business Ethics, Campus Recruitment, Career Development, Compensation, Drug Tests, Employee Relations, Flexible Benefits, Glass Ceiling, HR Metrics and Analytics, Mergers and Acquisitions, National Labor Relations Act, Quality Circles, Recruitment and Selection, Self-Directed Work Teams, Social Responsibility, Strategic Human Resource Management, Training Needs Analysis, Work Family Balance, and more. The Encyclopedia of Human Resource Management gives human resource professionals the knowledge, information, and tools needed to implement the best practices in the field.

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Adnan Tamime Y. Probiotic Dairy Products


Probiotic Dairy Products, 2nd Edition The updated guide to the most current research and developments in probiotic dairy products The thoroughly revised and updated second edition of Probiotic Dairy Products reviews the recent advancements in the dairy industry and includes the latest scientific developments in regard to the functional aspects of dairy and fermented milk products and their ingredients. Since the publication of the first edition of this text, there have been incredible advances in the knowledge and understanding of the human microbiota, mainly due to the development and use of new molecular analysis techniques. This new edition includes information on the newest developments in the field. It offers information on the new ‘omic’ technologies that have been used to detect and analyse all the genes, proteins and metabolites of individuals’ gut microbiota. The text also includes a description of the history of probiotics and explores the origins of probiotic products and the early pioneers in this field. Other chapters in this resource provide valuable updates on genomic analysis of probiotic strains and aspects of probiotic products’ production and quality control. This important resource: Offers a completely revised and updated edition to the text that covers the topic of probiotic dairy products Contains 4 brand new chapters on the following topics: the history of probiotics, prebiotic components, probiotic research, and the production of vitamins, exopolysaccharides (EPS), and bacteriocins Features a new co-editor and a host of new contributors, that offer the latest research findings and expertise Is the latest title in Wileys Society of Dairy Technology Technical Series Probiotic Dairy Products is an essential resource for dairy scientists, dairy technologists and nutritionists. The text includes the results of the most reliable research in field and offers informed views on the future of, and barriers to, the progress for probiotic dairy products.

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William J. Rothwell The Encyclopedia of Human Resource Management, Volume 3


The three volumes in The Encyclopedia of Human Resource Management offer a comprehensive review of the essential issues and most important information available on the topic. Each volume in the encyclopedia contains contributions from some of the most celebrated names in the field of human resource management (HRM) and addresses the myriad challenges faced by todays human resource professionals. Volume 3 highlights three main topics HR professionals have identified as critical issues in todays workplace: Leadership and Learning; Strategy and Measurement; and The Evolution of Human Resources. Many of the articles in this volume provide an in-depth discussion of a current human resource topic while others introduce a new way of approaching a familiar HR challenge. Each article is designed to stimulate critical thinking and reflection. The topics covered include: Best Practices in Leadership Development; Leadership is Going Global; Web 2.0 Applications in Corporate Training; The Social Construction of Productive Organizations; Leadership Versatility; Strategy and Measurement; Strategic Business Partner Role; Human Resource Metrics; The HR Transition to Strategic Partner; Workplace Bullying; Lost Wisdom, Lost ROI; The Role of HR in Fostering Innovation in Organizations; Closing Critical Skills Gaps; Employee Engagement and Corporate Social Responsibility; The Implications of Situational Strength for HRM; and more. The Encyclopedia of Human Resource Management gives human resource professionals the knowledge, information, and tools needed to implement the best practices in the field.

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Merline Lovelace A Man of His Word


Reece Henderson knew that the two most sacred things in life–the truth and a mans marriage vows–were also the hardest to stick to. So hed sworn to uphold the former and avoid the latter. Then beautiful Sydney Scotts return tested his promise.Ten years ago, Sydney had left in disgrace. Now she was back, determined to do the job shedbeen hired to do and move on. But she hadnt counted on Reece Henderson. He got her thinking that maybe, with the right man by her side, she could go home again….

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William J. Rothwell Encyclopedia of Human Resource Management, Resources and Employment Forms


The three volumes in The Encyclopedia of Human Resource Management offer a comprehensive review of the essential issues and most important information available on the topic. Each volume in the encyclopedia contains contributions from some of the most celebrated names in the field of human resource management (HRM) and addresses the myriad challenges faced by todays human resource professionals. Volume 2 highlights human resource management forms. The book contains a tool that can be used to build HR forms as well as processing transactions and measuring effectiveness. The books many field-tested forms can be downloaded, modified, and used immediately. The contributors also present a view of HR forms that help when planning for an audit and compliance activities and reporting on human resource effectiveness. The HR forms include: Interview Assessment Forms, New Employee Orientation Checklist, Blended Learning Program Review Form, Education Workshop Form, Talent Management Form, Job Analysis Worksheet Form, Manager Performance Evaluation Form, 360 Degree Feedback Form, Salary Change Form, Reporting Injury/Accident Form, Employee Disability Verification Form, Human Resource Metrics Form, and much more. The Encyclopedia of Human Resource Management gives human resource professionals the knowledge, information, and tools needed to implement the best practices in the field.

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Wendy James Early Human Kinship. From Sex to Social Reproduction


Early Human Kinship brings together original studies from leading figures in the biological sciences, social anthropology, archaeology, and linguistics to provide a major breakthrough in the debate over human evolution and the nature of society. A major new collaboration between specialists across the range of the human sciences including evolutionary biology and psychology; social/cultural anthropology; archaeology and linguistics Provides a ground-breaking set of original studies offering a new perspective on early human history Debates fundamental questions about early human society: Was there a connection between the beginnings of language and the beginnings of organized kinship and marriage? How far did evolutionary selection favor gender and generation as principles for regulating social relations? Sponsored by the Royal Anthropological Institute of Great Britain and Ireland in conjunction with the British Academy

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In this engaging dialogue, Zygmunt Bauman, sociologist and philosopher, and Stanislaw Obirek, theologian and cultural historian, explore the place of spirituality and religion in the world today and in the everyday lives of individuals. Their conversation ranges from the plight of monotheistic religions cast onto a polytheistic world stage to the nature of religious experience and its impact on human worldviews and life strategies; from Messianic and Promethean ideas of redemption and salvation to the possibility and prospects of inter-religious dialogue and the factors standing in its way. While starting from different places, Bauman and Obirek are driven by the same concern to reconcile the multiplicity of religions with the oneness of humanity, and to do so in a way that avoids the trap of adhering to a single truth, bearing witness instead to the multiplicity of human truths and the diversity of cultures and faiths. For everything creative in human existence has its roots in human diversity; it is not human diversity that turns brother against brother but the refusal of it. The fundamental condition of peace, solidarity and benevolent cooperation among human beings is a willingness to accept that there is a multiplicity of ways of being human, and a willingness to accept the model of coexistence that this multiplicity requires.

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The fourth edition of the Handbook of Human Factors and Ergonomics has been completely revised and updated. This includes all existing third edition chapters plus new chapters written to cover new areas. These include the following subjects: Managing low-back disorder risk in the workplace Online interactivity Neuroergonomics Office ergonomics Social networking HF&E in motor vehicle transportation User requirements Human factors and ergonomics in aviation Human factors in ambient intelligent environments As with the earlier editions, the main purpose of this handbook is to serve the needs of the human factors and ergonomics researchers, practitioners, and graduate students. Each chapter has a strong theory and scientific base, but is heavily focused on real world applications. As such, a significant number of case studies, examples, figures, and tables are included to aid in the understanding and application of the material covered.

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This update to the award-winning The Origins of Modern Humans: A World Survey of the Fossil Evidence covers the most accepted common theories concerning the emergence of modern Homo sapiens—adding fresh insight from top young scholars on the key new discoveries of the past 25 years. The Origins of Modern Humans: Biology Reconsidered allows field leaders to discuss and assess the assemblage of hominid fossil material in each region of the world during the Pleistocene epoch. It features new fossil and molecular evidence, such as the evolutionary inferences drawn from assessments of modern humans and large segments of the Neandertal genome. It also addresses the impact of digital imagery and the more sophisticated morphometrics that have entered the analytical fray since 1984. Beginning with a thoughtful introduction by the authors on modern human origins, the book offers such insightful chapter contributions as: Africa: The Cradle of Modern People Crossroads of the Old World: Late Hominin Evolution in Western Asia A River Runs through It: Modern Human Origins in East Asia Perspectives on the Origins of Modern Australians Modern Human Origins in Central Europe The Makers of the Early Upper Paleolithic in Western Eurasia Neandertal Craniofacial Growth and Development and Its Relevance for Modern Human Origins Energetics and the Origin of Modern Humans Understanding Human Cranial Variation in Light of Modern Human Origins The Relevance of Archaic Genomes to Modern Human Origins The Process of Modern Human Origins: The Evolutionary and Demographic Changes Giving Rise to Modern Humans The Paleobiology of Modern Human Emergence Elegant and thought provoking, The Origins of Modern Humans: Biology Reconsidered is an ideal read for students, grad students, and professionals in human evolution and paleoanthropology.

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More Max The Transhumanist Reader. Classical and Contemporary Essays on the Science, Technology, Philosophy of Human Future


The first authoritative and comprehensive survey of the origins and current state of transhumanist thinking The rapid pace of emerging technologies is playing an increasingly important role in overcoming fundamental human limitations. Featuring core writings by seminal thinkers in the speculative possibilities of the posthuman condition, essays address key philosophical arguments for and against human enhancement, explore the inevitability of life extension, and consider possible solutions to the growing issues of social and ethical implications and concerns. Edited by the internationally acclaimed founders of the philosophy and social movement of transhumanism, The Transhumanist Reader is an indispensable guide to our current state of knowledge of the quest to expand the frontiers of human nature.

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Ralph Garcia-Bertrand Genomes, Evolution, and Culture. Past, Present, Future of Humankind


This book combines recent information and discoveries in the field of human molecular biology and human molecular evolution. It provides an interdisciplinary approach drawing together data from various diverse disciplines to address both the more classical anthropological content and the current more contemporary molecular focus of courses. Chapters include a history of human evolutionary genetics; the human genome structure and function; population structure and variability; gene and genomic dynamics; culture; health and disease; bioethics; future.

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Barry Bogin Human Biology. An Evolutionary and Biocultural Perspective


This comprehensive introduction to the field of human biology covers all the major areas of the field: genetic variation, variation related to climate, infectious and non-infectious diseases, aging, growth, nutrition, and demography. Written by four expert authors working in close collaboration, this second edition has been thoroughly updated to provide undergraduate and graduate students with two new chapters: one on race and culture and their ties to human biology, and the other a concluding summary chapter highlighting the integration and intersection of the topics covered in the book.

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William J. Ray Abnormal Psychology


In&nbsp;<em>Abnormal Psychology: Perspectives on Human Behavior and Experience Second Edition,&nbsp;</em>William J. Ray brings together current perspectives concerning the manner in which the human mind, behavior, and experience can be understood. In addition to the traditional psychological literature, this book draws from work in the cognitive and affective neurosciences, epidemiology, ethology, and genetics. Ray's focus is on a unification and integration of the biopsychosocial understandings of human behavior within a broader consideration of human culture and language as it applies to abnormal psychology.

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Overwriting the human consciousness in the processor, UFOs and the presence on Earth of representatives of another civilization, obtaining information from the planet NOOSPHERE, the amazing possibilities of the human mind, the solution of events and phenomena that the official science can not explain, archaeological artifacts that overturn all scientific versions of human development civilization on the planet.

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John Hallward Gimme! The Human Nature of Successful Marketing


In Gimme!, advertising research expert John Hallward shows you how the most effective advertising campaigns tap into our most basic, primal emotions to convince consumers to buy. For marketers and advertisers, this book looks at the human nature of consumers and presents the proven tactics, techniques, and arguments that best motivate the human animal to buy.

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Mars is in crisis. Ten years after its formation the Earth colony on the red planet has yet to produce a healthy child. Every baby has been deformed and stillborn. With Earth overpopulated and at war, the success of the Mars experiment is crucial to the survival of the human race. Something must be done to ensure its future.In Finches of Mars, Brian Aldiss has produced a fascinating and thought-provoking novel that considers the practicalities of man’s exploration of space. It is shot through with the trademark wit and visionary philosophy which have been ever present across the seven decades of his writing career.

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Learn about the human body from the inside out Some people think that knowing about what goes on inside the human body can sap life of its mystery—which is too bad for them. Anybody whos ever taken a peak under the hood knows that the human body, and all its various structures and functions, is a realm of awe-inspiring complexity and countless wonders. The dizzying dance of molecule, cell, tissue, organ, muscle, sinew, and bone that we call life can be a thing of breathtaking beauty and humbling perfection. Anatomy & Physiology For Dummies combines anatomical terminology and function so youll learn not only names and terms but also gain an understanding of how the human body works. Whether youre a student, an aspiring medical, healthcare or fitness professional, or just someone whos curious about the human body and how it works, this book offers you a fun, easy way to get a handle on the basics of anatomy and physiology. Understand the meaning of terms in anatomy and physiology Get to know the bodys anatomical structures—from head to toe Explore the bodys systems and how they interact to keep us alive Gain insight into how the structures and systems function in sickness and health Written in plain English and packed with beautiful illustrations, Anatomy & Physiology For Dummies is your guide to a fantastic voyage of the human body.

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